Abstract

Background. To determine risk factors that influence peritonitis event on patients with Continuous Ambulatory Peritoneal Dialysis (CAPD) in Sanglah Hospital, thus, we can prevent the occurrence of peritonitis in CRF patients with CAPD.
 Methods. This is a retrospective cohort study, which was conducted at the Sanglah Hospital in Denpasar from August to September 2016. All data are processed using SPSS 17.0 for Windows, data analysis by using the Kaplan Meier (K-M) curves, hypothesis using the log-rank test, while for the survival is by using the median or mean survival. The significance is determined by the value of p < 0.05 with 95% CI.
 Results. A total of 78 people (46 men and 32 women) who meet the inclusion criteria of this study. Thirteen people (16.7%) are experiencing peritonitis. K-M Survival Curves between in CRF patients with CAPD, with Age ≥ 50 years (51.36 months survival rates, 95% CI 44.79 until 57.93) with < 50 years (56.1 months Survival rates, 95% CI 51.41 until 60.78) with RR 2.54 log-rank p 0.084. K-M Survival Curves between in CRF patients with CAPD, with DM (mean 52.63 months survival rates, 95% CI 47.21 until 58.06) with No DM (56.88 months survival rates, 95% CI 52.89 until 60.88) with RR 4.16 and 0.037 log-rank p.
 Conclusion. There is a correlation between DM and the incidence of peritonitis in CRF patients with CAPD at Sanglah Hospital. However, age and education level are not related.

Highlights

  • Chronic Renal Failure (CRF) or end-stage renal disease (ESRD) is a clinical condition characterized by an irreversible decline in kidney function, to a degree that requires renal replacement therapy in the form of dialysis or kidney transplantation

  • This study addressed the incidence of peritonitis as a complication of Continuous Ambulatory Peritoneal Dialysis (CAPD) therapy in CRF, is still a problem that needs attention because of the high morbidity rate.[5]

  • This non-significant result was consistent with studies in Aracaju, Brazil, between January 2003 and December 2007, which stated that there was no significant difference between the peritonitis with a factor of gender, age, income level, and diabetes mellitus.[6]

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Summary

Introduction

Chronic Renal Failure (CRF) or end-stage renal disease (ESRD) is a clinical condition characterized by an irreversible decline in kidney function, to a degree that requires renal replacement therapy in the form of dialysis or kidney transplantation. There is controversy over the results of research in these countries, which underpins the present study, whether the characteristics and risk factors of peritonitis in patients receiving CAPD therapy in Bali are similar or different according to the literature.

Results
Conclusion
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