Abstract

 
 
 
 Purpose: To evaluate the factors influencing deep vein thrombosis (DVT) in stroke patients, and the effect of anticoagulant intervention.
 Methods: A total of 208 stroke patients in Jiaozhou Central Hospital of Qingdao from March 2018 to March 2020 were assigned to DVT group (n = 84) and non-DVT group (n = 124). Their clinical data were analyzed to identify risk factors. Thereafter, the DVT group were randomized to control group and study group (n = 42 each). Conventional treatment and low molecular heparin plus treatment were given to the groups, respectively. Activities of daily living (ADL) and treatment outcomes were compared.
 Results: Univariate analysis showed that age, smoking history, Wells score, duration of bed rest, limb immobilization time after interventional therapy, D-dimer and TGs differed between the two groups (p < 0.05). Multivariate logistic regression analysis revealed that age ≥ 60 years old, smoking history, Wells score ≥ 2 points, duration of bed-rest ≥ 7 days, limb immobilization time ≥ 1 day after intervention, D- dimer < 0.95 mg/L and TG < 1.84 mmol/L were risk factors for DVT. After treatment, ADL and total treatment effectiveness in the study group were higher than in the control group (p < 0.05).
 Conclusion: Age ≥ 60 years, smoking history, Wells score ≥ 2 points, duration of bedrest ≥ 7 days, limb immobilization time ≥ 1 day after intervention, D-dimer < 0.95 mg/L and TG < 1.84 mmol/L are risk factors for DVT. The anticoagulant used (rivaroxaban) seems to improve daily living and reduce clinical symptoms.
 
 
 
Highlights
In recent years, the incidence of stroke has been on the rise in China, and it is characterized by high disability and mortality [1]
The following categories of patients were included in this study: (a) patients who met the diagnostic criteria for stroke [7], and patients diagnosed for stroke using Computerized Tomography (CT), CT angiography (CTA), and Magnetic Resonance Imaging (MRI); (b) patients with complete clinical data; (c) stroke patients aged ≥ 18 years; (d) patients admitted within 72 h of onset of stroke, and (e) patients with no history of allergy or contraindications to anticoagulant drugs
Multivariate logistic regression analysis revealed that age ≥ 60 years old, smoking history, Wells score ≥ 2 points, duration of bed rest ≥ 7 days, limb immobilization time ≥ 1 day after interventional therapy, D-dimer
Summary
The incidence of stroke has been on the rise in China, and it is characterized by high disability and mortality [1]. One of the common complications of stroke is deep vein thrombosis (DVT) of the lower extremities which ranks third in severity after coronary artery disease and cerebrovascular disease [2]. Deep vein thrombosis (DVT) is caused by blood. Anticoagulant drugs are frequently used for the treatment of stroke patients with DVT in the lower limbs. To date, there are no studies on factors that influence stroke with lower limb DVT in patients, as well as the effect of anticoagulant intervention. This study was aimed at identifying factors that influence lower extremity DVT in stroke patients, using 208 stroke patients diagnosed and confirmed in Jiaozhou Central Hospital of Qingdao from March 2018 to March 2020
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
