Factors Predicting the Quality of Total Mesorectal Excision in Asian Patients With Rectal Cancer

Abstract

predictive of an SVR (OR, 7.5; 95% CI, 1.33–42.27, P 1⁄4 .022). Nevertheless, an abbreviated regimen became the single factor associated with an SVR if treatment regimen was taken into consideration (OR, 11.0; 95% CI, 1.25–96.79, P 1⁄4 .031). The SVR rate was significantly higher (95.5% vs 75.0 %, P 1⁄4 .002) and the relapse rate was significantly lower (4.5 % vs 21.4 %, P 1⁄4 .01) in patients with an abbreviated regimen. The SVR rate did not differ between patients with rs8099917 TT and TG/ GG genotype (91.7% vs 87.5%, P 1⁄4 .63). CONCLUSIONS: The efficacy of pegylated interferon plus ribavirin therapy in patients with HCV 1/2 was satisfactory. The role of IL-28B genetic variants in the population may be limited.