Abstract

We reported here, the synthesis of a new N-heterocyclic chitosan derivative with N,N’-diphenacyl-4,4’-dipyridinium dibromide salt-core to improve the chitosan biological activity. Chemical modifications of chitosan are required to enhance its low solubility in aqueous solutions. The synthesis of functionalised chitosan with quaternary ammonium salt of dipyridinium, was carried out in aqueous medium, in the temperature range 20°C - 80°C, along the time up to 120 min (15-120 min.). The new chitosan derivative structure was characterised by XRD and FT-IR analysis of the solid samples, kept at ambient temperature and, also, by elemental analysis (C and N). The results show that the chitosan functionalised structure is influenced mostly by the temperature. The new compound could show promising biological properties due to improved solubility properties and deserves to be further investigatedfor various biological applications.

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