Factors of adherence to treatment with trospium in employees

Abstract

AimTo conduct a comprehensive study of adverse factors and decreasing patients’ adherence during treatment with trospium. Materials and methodsDuring 12 months, 977 patients receiving trospium were studied regarding demographic, socioeconomic, and medical parameters by studying employer’s records, extracts from income tax returns, questionnaires OABq-SF, MOS SF-36, ICIQ-SF, and questionnaires concerning demographic and social status, voiding diaries, and uroflowmetry. ResultsIn total, 54.4% and 35.5% of patients preserved adherence to treatment with trospium during 6 months and 12 months, respectively. The average time of reaching a 30-day break in trospium administration was 182 days. Patients diagnosed with urge urinary incontinence and overactive bladder OAB (56.1%; 40.7%), having severe incontinence symptoms (56.1%), showing objectively high treatment efficacy (25.3%), and individuals subjectively satisfied with treatment outcome (57.5%) prevail among adherent patients, a significant minority is heavy coffee drinkers (14.5%).Individuals who are healthcare and education employees having annual and monthly income significantly higher than the mean income of patients receiving trospium also prevail among adherent patients (25.0%; 32.5%). Adherent patients are significantly older (56.3) than patients less adherent to the treatment. ConclusionThis experiment allowed for the first time the determination of the complexity of heterogeneous medical, socioeconomic, and demographic factors affecting patients’ adherence in treatment with trospium.