Factors influencing the incidence of preoperative deep venous thrombosis in patients with multiligament knee injuries

Abstract

Objective To determine the factors influencing the incidence of preoperative deep venous thrombosis (DVT) in patients with multiligament knee injuries.Methods From June 2007 to December 2010,134 consecutive patients with multiligament knee injuries were admitted to our department.Of them,130 were included in our study.They were 102 men and 28 women,with an average age of 35.8 ± 3.8 years and an average body mass index (BMI) of 24.5 ±4.3 kg/m2.According to the incidence of preoperative DVT,they were divided into a DVT group and a non-DVT group.The 2 groups were compared in terms of gender,age,BMI,cause of injury,interval between injury and inspection,combined lower limb fracture,injury severity score(ISS),smoking and results of hematologic tests (D-dimer,blood platelet count,triglyceride and fibrinogen).Multifactor logistic regression analysis was conducted of the factors of P ＜ 0.05 to determine the independent risk factors.Results Of the 130 patients,12 (9.2％) were diagnosed with DVT.The 2 groups were not significantly different regarding gender,age,BMI,cause of injury,interval between injury and inspection,smoking,ISS,or triglyceride level (P ＞ 0.05).However,there were significant differences between the 2 groups regarding combined lower limb fracture,D-dimer level,blood platelet count,and fibrinogen level(P ＜ 0.05).The logistic regression analysis showed that D-dimer level,increased fibrinogen level,and complication with lower limb fracture were the independent risk factors of DVT(P ＜0.05).Conclusions The incidence of preoperative DVT in patients with multiligament knee injuries was about 9.2％ in our study.D-dimer level,increased fibrinogen level and complication with lower limb fracture are independent risk factors of preoperative DVT in such patients. Key words: Venous thrombosis; Knee joint; Ligaments, articular; Factor analysis, statistical