Abstract
Diarrhea is a mild condition, able to be treated with self-medication. There are factors that influence self-medication behavior, including predisposing factors such as knowledge and attitudes. This research aimed to examine the effect of influencing factors such as attitudes and knowledge on the behavior of self-medication in diarrhea treatment and to determine which factors have the most influence in Kauman Village, Srengat District, Blitar Regency. This was quantitative research with a descriptive observational approach and cross-sectional design. This research adopted the quota sampling method and selected 100 respondents. Data were analyzed using descriptive analysis, normality tests and the Chi-square test. According to the findings, there was a good level of knowledge (91%), positive attitudes (57%), and appropriate behavior (56%) among the respondents. There was a significant correlation between knowledge and self-medication behavior (p = 0.016) and between attitudes and self-medication behavior (p < 0.001).
 Keywords: self-medication, diarrhea medicine, health behavior
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