Abstract

Aim: Chronic kidney disease (CKD) is an emerging major public health issue that leads to end-stage kidney disease (ESRD). Factors influencing the self-management and self-efficacy of ESRD patients are still under investigation. The objective of this study is to evaluate the association of depression and anxiety with self-management and self-efficacy in patients with pre-ESRD. Methods: Patients in the department of nephrology of a regional hospital in Taiwan were invited to participate and were included in our study if they had a confirmed diagnosis of early-stage CKD, were more than 20 years old, and could converse in Mandarin Chinese or Taiwanese. Patients diagnosed with depression, who could not execute self-care, or who had cognitive deficits were excluded. In total, this cross-sectional study included 112 pre-ESRD patients. We used the Chinese versions of the hospital anxiety and depression scale (HADS), the chronic kidney disease self-efficacy instrument (CKD-SE), and the chronic kidney disease self-management instrument (CKD-SM) as the questionnaire. Spearman’s rank correlation and logistic regressions were used to analyze the data. Results: The top quartile of self-management and self-efficacy scores (28 patients) was defined as high self-management and -efficacy, respectively, and the lower three quartiles as low self-management and -efficacy. The logistic regression analysis showed that having depression decreased the odds of having high self-management by 75.4% and high self-efficacy by 75.1%. Having an education level of senior high school or above increased the odds ratios for having high self-management and high self-efficacy to 4.47 and 3.56 (all p-values < 0.05). Conclusion: Controlling depression as well as increasing the level of education can potentially increase self-management and self-efficacy in pre-ESRD patients.

Highlights

  • Chronic kidney disease (CKD) is an important and prevalent disease that is emerging as a major public health issue

  • CKD places a large burden on the medical system since it leads to end-stage renal disease (ESRD), which can significantly reduce the quality of life and is associated with a high mortality rate

  • Psychiatric disorders commonly co-exist with CKD and ESRD, and this may explain the high prevalence of depression and anxiety in ESRD patients [4]

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Summary

Introduction

Chronic kidney disease (CKD) is an important and prevalent disease that is emerging as a major public health issue. CKD places a large burden on the medical system since it leads to end-stage renal disease (ESRD), which can significantly reduce the quality of life and is associated with a high mortality rate. Common treatment options for ESRD include maintenance haemodialysis, regular attendance at a dialysis center, adhering to fluid-intake protocols, medications, and lifestyle changes. Poor adherence to these treatments and lifestyle changes results in an increase in mortality and morbidity. The psychological and social stress associated with the condition influence survival rate and reduce quality of life [3]. Psychiatric disorders commonly co-exist with CKD and ESRD, and this may explain the high prevalence of depression and anxiety in ESRD patients [4]. In addition to physical and nutritional impairment, old age, and heart failure, depression is considered a major risk factor for mortality in these patients [5]

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