Abstract
To the Editor: The implementation of iPLEDGE, a program requiring women of childbearing potential to make a monthly pledge to use 2 forms of contraception while taking isotretinoin, did not significantly reduce the risk of fetal exposure to isotretinoin,1 with approximately 150 isotretinoin-exposed pregnancies occurring annually from 2008 to 2011.2 Numerous studies have demonstrated that these pregnancies are linked to poor adherence to contraception.2-4 The most effective reversible birth control methods are the long-acting reversible contraceptives (LARCs), which include intrauterine contraception and subdermal implants.
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