Abstract

Background: The COVID-19 pandemic has raised the necessity to rapidly develop safe and effective vaccines to limit the spread of infections. Meanwhile, vaccine hesitancy is a significant barrier to community vaccination strategies. Methods: An internet-based cross-sectional survey was conducted from March to April 2021 during the start of the vaccination campaigns. Results: A total of 1009 subjects participated, and the mean age (±SD) was 29.11 ± 8.2 years. Among them, 68.8% believed that vaccination is an effective method to control the spread of the disease, 81.2% indicated acceptance of the vaccine, and 87.09% reported that their doctor’s recommendation was essential for decision making. After adjusting for socioeconomic characteristics, rural residency (AOR 1.783, 95%CI: 1.256–2.531), working a part-time job (AOR 2.535, 95%CI: 1.202–5.343) or a full-time job (AOR 1.951, 95%CI: 1.056–3.604), being a student (AOR 3.516, 95%CI: 1.805–6.852) and having a partner (AOR 1.457, 95%CI: 1.062–2.00) were significant predictors for higher vaccine acceptance among the study participants. Believing in the vaccine’s efficacy showed the strongest correlation with vaccine acceptance (Spearman’s r = 0.309, p < 0.001). Conclusions: Although general vaccine acceptance is high (32.85%) in participants in our study, gender and geographic disparities were observed in the investigated urban population of young, well-educated Egyptians.

Highlights

  • The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the emergence of the ongoing coronavirus disease 2019 (COVID-19) pandemic [1,2,3,4]

  • This study aims to assess the COVID-19 vaccine acceptance among an Egyptian sample, highlight the factors that may influence the decision to be vaccinated against COVID-19 and raise more attention to the importance of identifying such factors

  • After adjusting for socioeconomic characteristics, rural residency (AOR 1.783, 95%CI: 1.256–2.531, p = 0.001), working a part-time job (AOR 2.535, 95%CI: 1.202–5.343 p = 0.015) or a full time job (AOR 1.951, 95%CI: 1.056–3.604, p = 0.033), being a student (AOR 3.516, 95%CI: 1.805–6.852, p < 0.001) and having a partner (AOR 1.457, 95%CI: 1.062–2, p = 0.02) were significant predictors for higher vaccine acceptance among study participants

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Summary

Introduction

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the emergence of the ongoing coronavirus disease 2019 (COVID-19) pandemic [1,2,3,4]. The COVID-19 outbreak raised the necessity to rapidly develop efficient and safe vaccines to limit the spread of this infection [7]. A worldwide race to develop a vaccine against SARS-CoV2 started after the emergence of the COVID-19 pandemic [14]. The COVID-19 pandemic has raised the necessity to rapidly develop safe and effective vaccines to limit the spread of infections. 68.8% believed that vaccination is an effective method to control the spread of the disease, 81.2% indicated acceptance of the vaccine, and 87.09% reported that their doctor’s recommendation was essential for decision making. Conclusions: general vaccine acceptance is high (32.85%) in participants in our study, gender and geographic disparities were observed in the investigated urban population of young, well-educated Egyptians

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