Abstract
To evaluate risk factors for gallstones after gastrectomy. To identify documents published from 1990 to 2011 the Pubmed, Cochrane Library, Springer Link, CBM and WanFang databases were searched and a meta-analysis was performed with RevMan 5.2 software for odds ratios and 95%CIs. Fifteen studies were selected for the meta-analysis. The pooled ORs [95%CIs] were 0.56 [0.43, 0.73], (P<0.0001) for digestive tract reconstruction, 0.80 [0.54, 1.17], (P=0.25) for pylorus preservation, 0.33[0.15, 0.75], (P=0.008) for resection scope of stomach, 0.33 [0.15, 0.75], (P=0.008) for lymphadenectomy, and 0.13 [0.05, 0.33], (P<0.0001) for vagotomy. Digestive tract physical reconstruction and vagus nerve preservation can reduce the morbidity of gallstones after gastrectomy. Total gastrectomy can add to the morbidity of galltones as does increasing the degree of lymph node dissection. There was no significant difference in gallstones with or without pylorus preservation.
Highlights
The surgery is the preferred treatment method of gastric cancer
The results showed that the incidence of postoperative gallstone in total gastrectomy was higher than that of distal gastrectomy
The results showed that the incidence of postoperative gallstone in vagus nerve-preserving group was lower than that of vagus nerve-cutting off group
Summary
The surgery is the preferred treatment method of gastric cancer. With the mature of surgical techniques and postoperative comprehensive treatment, the survival time of patients with gastric cancer was greatly extended after surgery; the postoperative complications have been paid more and more attention. The gallstone occurrence after gastric cancer operation was extensively studied, researcher found that the gallstone occurrence was related to the following factors: whether cutting off vagus nerve, the dissection degree of lymph node, the scope of gastrectomy, the reconstruction way of digestive tract, whether pylorus-preserving, etc; some scholars still have different opinions. We used Meta-analysis to comprehensive quantitative analyze the research literature of postoperative gallstone of gastric cancer at home and abroad, explore their relationships and mechanisms, which provide a theoretical basis for the prevention and treatment of gallstones after gastric cancer operation
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