Abstract

BackgroundOne third of all head and neck cancers are caused by laryngeal cancer. However, the incidence and prevalence rates have decreased over the past 3 decades. Neck metastasis from cancer larynx is important to be addressed as its presence greatly reduces the probability of survival. However, quality of life should be taken into consideration. Hence, it was important to analyze factors related to neck metastasis from primary laryngeal cancer to detect any change of tumor behavior with time.ResultsOne hundred thirty-eight patients underwent concomitant neck dissection with laryngectomy (total or partial). Supraglottic tumors had the greatest share in the neck metastasis with a count of 11 (of 26 neck metastasis), representing 42% and a total value of 11 (of 30 total supraglottic cancer) representing a tendency of spread in 37% of the total case number. Tumor midline crossing was present in 77% cases (20 of 26) with positive nodes, representing a P value 0.05.ConclusionThis study investigated different factors related to lymph node metastasis from primary laryngeal tumor. The most important factors were the site of the tumor and its relation to the midline.

Highlights

  • One third of all head and neck cancers are caused by laryngeal cancer

  • * Correspondence: Dr.mottaleb@gmail.com ENT Department, Cairo University, Al-Saray Street, El Manial, Cairo 11562, Egypt neck metastasis from primary laryngeal cancer to detect any change of tumor behavior with time

  • Included patients were analyzed for the tumor site, side, size, shape type, differentiation, midline crossing, and lymph node metastasis

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Summary

Introduction

One third of all head and neck cancers are caused by laryngeal cancer. the incidence and prevalence rates have decreased over the past 3 decades. Quality of life should be taken into consideration. It was important to analyze factors related to neck metastasis from primary laryngeal cancer to detect any change of tumor behavior with time. In 2017, 210,606 new cases of cancer larynx were recorded worldwide, and the prevalence was 1.09 million cases. Primary laryngeal cancer arises from glottic, supraglottic, subglottic, or transglottic regions [2]. Neck metastasis from cancer larynx is important to be addressed as its presence greatly reduces the probability of survival [3]. The quality of life should be taken into consideration. It was important to analyze factors related to

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