Factors associated with urosepsis following percutaneous nephrolithotomy

Abstract

Objective: To evaluate factors associated with urosepsis after percutaneous nephrolithotomy (PCNL). Materials and Methods: Seventy-six upper tract urinary calculi patients underwent PCNL at Loei Hospital between July 2014 to January 2019, all were enrolled onto the study. The following data were collected: demographics, type and size of stone, intraoperative data, pelvic urine culture and urosepsis complications after the procedure. Association of factors with urosepsis after PNCL were identified using a binary logistic regression model with a bootstrap estimation. Results: Urosepsis complications occurred in 7 patients (9.2%). Mean (SD) of age was 54.4 (10.3) years. Of all patients, 2% with staghorn stone and 22% positive urine culture. Multivariable analysis indicated that staghorn stone (a OR =6.75; 95%CI: 1.59-28.63, p=0.01) and positive pelvic urine culture (a OR =7.51; 95%CI: 1.35-41.77, p=0.02) were associated with urosepsis after PCNL. Conclusion: There was no mortality after PCNL in this study. Staghorn stone and positive pelvic urine culture may be associated with an increased risk of urosepsis complication.