Abstract

A variety of laryngeal pathologies are increasingly being managed with in-office KTP laser (IOKTP) endoscopic procedures. The primary goal of this study was to identify patient characteristics and disease-related features that correlated with tolerance for IOKTP. Retrospective chart review. The study was a retrospective review of adult patients undergoing office-based laryngeal laser procedures between November 2016 and December 2019 at a tertiary care center. Two blinded otolaryngologist reviewers scored videotaped recordings of IOKTP procedures and assessed severity and distribution of disease using a modified Derkay score, and evaluated procedure tolerance using a visual analog scale. A total of 56 patients who received IOKTP procedures for laryngeal pathology were reviewed, 42 male and 14 female, with a mean age of 61 years. Gender, age, and BMI were not correlated with tolerance. There was a moderate, negative correlation between tolerance and total number of pathological anatomic laryngeal subsites (rs(56)=-0.35, P=.01). There was a weak, negative correlation between tolerance and total modified Derkay score (rs(56)=-0.29, P=.03). The median tolerance score was lower for patients with posterior lesions (Mdn=6.4) compared with patients with non-posterior lesions (Mdn=7.4), P=.04, and lower for current or former smokers (Mdn=6.5) compared with never smokers (Mdn=7.3), P=.04. Patients with large disease burden or posterior lesions and patients with smoking history may exhibit poorer tolerance of IOKTP procedures, factors which can help guide pre-procedural counseling and management decisions. IV Laryngoscope, 131:E2292-E2297, 2021.

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