Abstract

The presence of a positive margin after ablative surgery has therapeutic and prognostic implications in patients with oral cavity carcinoma. The intraoperative clinical assessment of tumor margins is difficult and the use of frozen section (FS) analysis helps guide the adequacy of the resection and allows for immediate revision of the operative bed when necessary. The aims of this study were to determine whether the need for immediate, repeated resection in patients with a positive FS margin, or the rate of diagnostic discrepancy between the FS analysis and the permanent section review was associated with tumor location, size, grade or node status.

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