Abstract

Objective To determine the effectiveness of trial of labor after cesarean section (TOLAC) and the factors associated with a successful TOLAC. Materials and Methods A retrospective cohort study was conducted on consecutive singleton pregnancies with a previous single low-transverse cesarean section planned for TOLAC at a tertiary teaching hospital. The potential risk factors of a successful TOLAC were compared with those associated with a failed TOLAC. A simple audit system used in the first two years was also taken into account in the analysis as a potential factor for success. Results During the study period, 2,493 women were eligible for TOLAC and 704 of them were scheduled for TOLAC, but finally 592 underwent TOLAC. Among them, 355 (60%) had a successful vaginal birth and 237 (40%) had a failed TOLAC. The independent factors associated with the success rate included the audit system, prior vaginal birth, low maternal BMI, and lower birth weight or gestational age, whereas induction of labor and recurring indications in previous pregnancy significantly increased the risk of having a failed TOLAC. Strikingly, the strongest predictor of a successful TOLAC was the audit system with OR of 6.4 (95%CI: 3.9-10.44), followed by a history of vaginal birth in previous pregnancies (OR: 3.2; 95%CI: 1.87-5.36). Conclusion The simple audit system had the greatest impact on the success rate of TOLAC, instead of the less powerful obstetrical factors as reported in previous reports. The audit system is the only potential factor that could be strengthened to improve the success rate.

Highlights

  • Women undergoing cesarean section have a higher morbidity and mortality rate than those having vaginal birth, such as massive postpartum hemorrhage, need for blood transfusion, anesthesia-associated complications, surgical risks, and obstetric complications in subsequent pregnancies

  • During the first two years of using this formal guideline, trial of labor after cesarean delivery (TOLAC) practice was audited by the simple audit system, as follows: (1) one of our doctors was responsible to give a monthly orientation on the TOLAC guideline as well as a counseling guide with visual aids to the team of physicians taking care of the antenatal clinic and the labor doctors, throughout the first two years; (2) the same doctor monthly reported the outcomes of TOLAC to the audit team and the rates of cesarean section, TOLAC, and successful/unsuccessful TOLAC of each doctor were exposed to the staff members of the department

  • This study indicates that the success rate of TOLAC was relatively low when compared to that of several previous publications (60-80%) [1, 4,5,6,7]

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Summary

Objective

To determine the effectiveness of trial of labor after cesarean section (TOLAC) and the factors associated with a successful TOLAC. The potential risk factors of a successful TOLAC were compared with those associated with a failed TOLAC. 355 (60%) had a successful vaginal birth and 237 (40%) had a failed TOLAC. The independent factors associated with the success rate included the audit system, prior vaginal birth, low maternal BMI, and lower birth weight or gestational age, whereas induction of labor and recurring indications in previous pregnancy significantly increased the risk of having a failed TOLAC. The strongest predictor of a successful TOLAC was the audit system with OR of 6.4 (95%CI: 3.9-10.44), followed by a history of vaginal birth in previous pregnancies (OR: 3.2; 95%CI: 1.87-5.36). The audit system is the only potential factor that could be strengthened to improve the success rate

Introduction
Materials and Methods
Result
Discussion
Findings
Conflicts of Interest
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