Abstract
Abstract Objectives: to compile studies produced regardinggenetic and non-genetic risks factors associated with occurrence of spontaneous abortion. Methods: it talks about a systematic review article, with studies between January of 2008 to November of 2018 according to SciELO, PubMed, Lilacs and BVS. Results: in total, 567 articles were found. After applying the definedeligibility criteria, 44 articles made part of the review, being the majority published on Asia between 2008 and 2011, and 10 articles published on Brazil. Not genetic causes like sociodemographic factors and healthy state were among the most associated conditions of spontaneous abortion. Asiatic continent had predominance about the correlation of spontaneous abortion with factors related to life style like obesity, smoking and labor activities, on the other hand, in the Americas, causes related to sociodemographics factors like low pay and low studies are high-lighted. Conclusions: the risk factors change about the occurrence region, being important to make local studies capable of subsidize the implantation of public politics and to reduce abortions.
Highlights
Spontaneous abortion is the most common gestational adversity and is often of unknown etiology
Given the above and the great variety of studies that addressed possible causes and risk factors about spontaneous abortion and, taking into account the variations related to the population and region studied, this study aimed to review the scientific knowledge produced in the last 10 years on the theme
When analyzing the 44 studies included in this review, it was observed that most of the articles were aimed at identifying factors related to idiopathic or recurrent spontaneous abortion
Summary
Spontaneous abortion is the most common gestational adversity and is often of unknown etiology. In most patients, it has a multifactorial cause, which difficult its investigation.[1,2,3] This problem is defined as the involuntary termination of pregnancy, up to 20-22 gestational weeks.[4] Its recurrent form is characterized by the loss of three or more pregnancies, consecutively.[2]. 15 to 20% end in spontaneous abortion, most within the first 13 weeks of pregnancy.[4,5] Among the consequences, the emotional and psychological damage to the couples involved stands out, with the risk of death of the pregnant woman as a result of complications, in addition to high costs to the public funds, constituting an important public health problem.[6]
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