Factors associated with intraoperative blood transfusion during meningioma surgery

Abstract

Objective This study was designed to identify the risk factors associated with intraoperative blood transfusion in patients undergoing meningioma resection, and establish a risk prediction model. Methods A retrospective analysis was performed using clinical data from 585 patients undergoing meningioma surgery at the First Affiliated Hospital of Fujian Medical University from January 2015 to December 2018. The univariate analysis and multivariate Logistic regression analysis were used to evaluate the risk factors for intraoperative blood transfusion and build a risk prediction model. Furthermore, the receiver operating characteristics curve (ROC) was plotted to calculate the area under the curve (AUC). Results There were 136 patients (23.25%) receiving intraoperative blood transfusion. The risk factors associated with intraoperative blood transfusion were skull base tumor (X1), tumor diameter≥3.7 cm (X2) and important blood vessel involvement(X3)(P<0.05). The predictive probability model was P=1/1+e-Y, Y=-3.602+0.596X1+2.163X2+1.809X3, where the AUC was 0.843±0.018(P<0.05). Conclusions Skull base tumor, tumor diameter≥3.7 cm and important blood vessel involvement are the independent risk factors of intraoperative blood transfusion during meningioma resection. Key words: Meningioma; Blood transfusion; Risk factors