Abstract
BackgroundNonelderly patients may require hospitalization if their symptoms of influenza are severe. However, little evidence is available about the risk factors for hospitalization for influenza.MethodsWe used a multicenter outpatient and inpatient database to obtain patients’ characteristics and clinical procedures. We identified patients aged <65 years with a confirmed diagnosis of influenza between October 2013 and December 2014. We used a Cox regression model to identify the risk factors for hospitalization, using a comparison group of individuals with a confirmed diagnosis of influenza but who were not hospitalized.ResultsOf 88,054 patients diagnosed with influenza, 276 (0.3 %) patients were hospitalized. With reference to patients aged 18–64 years, the hazard ratio (95 % confidence interval) for hospitalization in patients aged <2, 2–4, and 5–17 years was 12.25 (8.37–17.93), 4.56 (3.10–6.72) and 1.45 (1.03–2.05), respectively. Anemia, chronic obstructive pulmonary disease, neurologic disease, and regular steroid use were significantly associated with hospitalization. Hazard ratios were adjusted for age, sex, comorbidities, respiratory co-infection, virus type, and influenza season.ConclusionsOur findings suggest that younger age and several comorbidities are associated with higher probability of hospitalization for influenza.
Highlights
Patients may require hospitalization if their symptoms of influenza are severe
The aims of the present study were (i) to examine patient demographic characteristics, clinical courses, and complications, and (ii) to identify risk factors for hospitalization in patients aged
Case identification and clinical courses We identified patients aged
Summary
Patients may require hospitalization if their symptoms of influenza are severe. Little evidence is available about the risk factors for hospitalization for influenza. Owing to the rarity of fatal cases [2], especially in nonelderly patients, hospitalization for influenza has been the main focus of several studies [3] to make decisions about resource planning, such as stockpiling of. Data have been lacking on the risk factors for hospitalization, individuals at high risk for complicated influenza have been defined [6]. A systematic review in 2013 revealed that the risk factors for hospitalization for influenza were rarely investigated [6]. Ono et al BMC Public Health (2016) 16:922 hospitalization in 424 patients with laboratory-confirmed influenza who visited emergency departments [7]. Another study demonstrated that individuals with pulmonary disease, dementia, renal disease, or cancer had a higher likelihood of hospitalization among community-dwelling elderly people [8]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
