Abstract

In Benin Republic, few data are available on the prevalence and determinants of arterial hypertension (AH) in people living with the human immunodeficiency virus (PLWHA). The present study was conducted in two outpatient treatment centers for PLWHA in Cotonou and was conducted from June 19 to July 04, 2019 with 314 PLWHA. We performed descriptive statistics and logistic regression for the estimates. The prevalence of high blood pressure (HBP) among PLWHA was 41.4% [CI (95%): (35.9 - 47)]. In univariate analysis: age, smoking, alcoholism, physical inactivity, family history of hypertension, personal history of diabetes, obesity, and total and LDL (low density lipoprotein) hypercholesterolemia were significantly associated with HBP. No association was found with duration of HIV (human immunodeficiency virus) infection, time to ARV (antiretrovirals) exposure, and treatment regimen. In multivariate analysis, age, sex, smoking, family history of hypertension, and total hypercholesterolemia remained associated with HBP. In conclusion, the prevalence of HBP in PLWHA was very high compared with the results in the general population, and the same risk factors described in the general population were found but with a more marked hypertense potential.

Highlights

  • Survival period of people living with the human immunodeficiency virus (PLWHA) has improved considerably after the advent of triple antiretroviral therapy at the end of the 1990s [1]

  • In Benin Republic, few data are available on the prevalence and determinants of arterial hypertension (AH) in people living with the human immunodeficiency virus (PLWHA)

  • The prevalence of high blood pressure (HBP) in PLWHA was very high compared with the results in the general population, and the same risk factors described in the general population were found but with a more marked hypertense potential

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Summary

Introduction

Survival period of PLWHA has improved considerably after the advent of triple antiretroviral therapy at the end of the 1990s [1]. The word group “high blood pressure” (HBP) seems more appropriate in our context because of the cross-sectional nature of this study, which provides, to a certain extent, indicative information to estimate the prevalence of HBP in this group of patients, while allowing the identification of the factors associated with its occurrence. It has the merit of proposing approaches to solutions to perpetuate the notable advances in the organization of services offered to PLWHA through better management of blood pressure in these patients. Little is still known about the distribution and determinants of hypertension among PLWHA in Benin

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