Abstract

Four isolated cases of congenital syphilis born to mothers who screened syphilis negative in the first trimester were identified between March 2016 and January 2017 compared with three cases between 2010 and 2015. The mothers were United Kingdom-born and had no syphilis risk factors. Cases occurred in areas with recent increases in sexually-transmitted syphilis among women and men who have sex with men, some behaviourally bisexual, which may have facilitated bridging between sexual networks.

Highlights

  • Four isolated cases of congenital syphilis born to mothers who screened syphilis negative in the first trimester were identified between March 2016 and January 2017 compared with three cases between 2010 and 2015

  • Between March 2016 and January 2017 inclusive, we identified four apparently atypical Congenital syphilis (CS) cases that were caused by incident maternal syphilis infection after a negative first trimester antenatal screen

  • Syphilis remains rare in the general population: population-based blood donation data show that between and 2016, the rate of recent syphilis infection in the United Kingdom (UK) was 1.1 per 100,000 donations from men and

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Summary

Endemic areas

Cases were defined as confirmed following [3]. Time trend and time series analysis model for sexually transmitted infectious syphilis diagnoses by sexual orientation and syphilis epidemiological areas, England, January 2011–September 2016.

Rest of England
Discussion
Conflict of interest
Findings
Increase in Sexually Transmitted Infections among Men
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