Factors associated with complications from COVID-19 in hospital workers: A retrospective cohort study.

Abstract

SARS-CoV-2 infection in healthcare professionals represents a threat to the healthcare system. To identify factors associated with complications from COVID-19 in healthcare workers infected by SARS-CoV-2, in a specialized national hospital level III in Peru in 2020. This is a retrospective cohort study. Health personnel who were working at Instituto Nacional Materno Perinatal of Peru participated. The clinical and epidemiological characteristics and results of the Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) test were collected from the medical records and epidemiological files. Simple and multiple regression models were used to estimate the risk factors of complications due to COVID-19. We found 1048 suspected cases, and 26.2% had a confirmed SARS-CoV-2 infection. Of those infected, 20.8% had comorbidity, and 55% reported contact with COVID-19 patients in health care settings. Moreover, 27.4% of infected workers were administrative personnel, 24.1% were nursing technicians, 18.3% were nurses, and 13.1% were physicians. We also found that 24.1% presented complications from COVID-19, and three workers died. In a multiple regression, the risk factors for complications due to COVID-19 were the presence of comorbidity (risk ratio: 2.94; 95% confidence interval: 1.95 to 4.42), 30 years or older (1.28; 0.6 to 2.75), 60 years or older (2.04; 0.88 to 4.74), male sex (1.1; 0.71 to 1.7) and care work area (1.02; 0.06 to 2.62). The findings in the present study show an association between the presence of comorbidities and an increased risk of presenting complications due to COVID-19 in healthcare workers, regardless of age, sex and area of work.