Factors affecting quality of life in patients on haemodialysis: a cross-sectional study from Palestine.

Sa’Ed H Zyoud,Ghada H Tabeeb,Mayas N Sawafta,Samah W Al-Jabi,Rahmat Awang,Razan L Khdeir,Dala N Daraghmeh,Diana O Mezyed,Nora A Ayaseh,Waleed M Sweileh

doi:10.1186/s12882-016-0257-z

Sa’Ed H Zyoud, Ghada H Tabeeb + Show 8 more

Open Access

https://doi.org/10.1186/s12882-016-0257-z

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Abstract

BackgroundHaemodialysis (HD) is a life-sustaining treatment for patients with end-stage renal disease (ESRD). HD can bring about significant impairment in health-related quality of life (HRQOL) and outcomes. Therefore, we sought to describe the patterns of HRQOL and determine the independent factors associated with poor HRQOL in Palestinian patients on HD.MethodsA multicenter cross-sectional study was performed from June 2014 to January 2015 using the EuroQOL-5 Dimensions instrument (EQ-5D-5L) for the assessment of HRQOL. ESRD patients undergoing HD in all dialysis centres in the West Bank of Palestine were approached and recruited for this study. Multiple linear regression was carried out to identify factors that were significantly associated with HRQOL.ResultsTwo hundred and sixty-seven patients were participated in the current study giving response rate of 96 %. Overall, 139 (52.1 %) were male, and the mean ± standard deviation age was 53.3 ± 16.2 years. The reported HRQOL as measured by mean EQ-5D-5L index value and Euro QOL visual analogue scale (EQ-VAS) score was 0.37 ± 0.44 and 59.38 ± 45.39, respectively. There was a moderate positive correlation between the EQ-VAS and the EQ-5D-5L index value (r = 0.42, p < 0.001). The results of multiple linear regression showed a significant negative association between HRQOL with age, total number of chronic co-morbid diseases and the total number of chronic medications. However, a significant positive association was found between HRQOL with male gender, university education level and patients who live in village.ConclusionOur results provided insight into a number of associations between patient variables and their HRQOL. Healthcare providers should be aware of low HRQOL among patients with no formal education, female gender, patient’s residents of refugee camps, multiple co-morbid diseases, multiple chronic medications, and elderly patients to improve their quality of life.

Highlights

Haemodialysis (HD) is a life-sustaining treatment for patients with end-stage renal disease (ESRD)
Multiple linear regression was carried out to identify factors that were significantly associated with health-related quality of life (HRQOL)
Wasserfallen et al [49] showed that using a generic quality of live (QOL) instrument EQ-5D was well-accepted, and easy to use for assessing HRQOL among ESRD patients undergoing HD due to the shorter completion time compared with other generic instruments

Summary

Introduction

Haemodialysis (HD) is a life-sustaining treatment for patients with end-stage renal disease (ESRD). Chronic kidney disease (CKD) is a growing worldwide public health concern [1, 2]. It is characterised by an irreversible worsening of renal function that could lead to end-stage renal disease (ESRD), which necessitates treatment with renal replacement therapy (RRT) such as. Previous reports have confirmed that ESRD patients undergoing HD have lower health-related quality of life (HRQOL) compared with compared with a normative sample [11,12,13,14,15,16,17,18,19,20,21]. It has been shown that improving the quality of treatment in patients with ESRD can minimize the development and/or severity of complications and improve patients’ HRQOL [25,26,27]

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