Factors affecting prognosis after curative surgical treatment of gastric cancer

Abstract

Background: Gastric cancer is a cancer with a poor prognosis. Surgery with adequate lymph node dissection is the only potentially curative treatment for gastric cancer. The aim of this work is to determine the prognostic factors after curative resection for gastric cancer.Patients and Methods: We retrospectively assessed 66 patients who underwent operation for gastric cancer (excluding the eso gastric junction cancer) in a single institution between 2001 and 2015. Results: There were 25 women and 40 men. The median age was 60 years (21–87). Four patients died (6.1%). A total gastrectomy was performed in 35 cases, and a subtotal gastrectomy was performed in 30 cases. The type of lymphadenectomy was D2 lymphadenectomy in 35 cases and D2 without spl enectomy in 30 cases. The pathologic review of the slides revealed that the tumors were stage T3–T4 in 49 cases. The median number of lymph node removed was 14. Median survival rate was 34 months. The median follow-up was 24 months. In multivariate analysis, the location in the fundus, lymph nodes involvement, and involvement of located organs were associated with poor prognosis. Conclusion: After R0 resection with DII lymphadenectomy, fundus location, lymph node Involvement, and involvement of organs were independent predictive factors for survival.