Abstract
Objective To explore the factors affecting the adenoma risk level in patients with intestinal polyp and association. Methods The clinical data of 3,911 patients with intestinal polyp treated in our hospital from January 2018 to January 2021 were retrospectively analyzed, all patients accepted the histopathological examination, their risk of suffering from adenoma was evaluated according to the results of pathological diagnosis, and relevant hazard factors affecting adenoma risk level in them were analyzed by multifactor logistic regression analysis. Results The results of multifactor logistic analysis showed that male gender, age ≥60 years, number of polyps >3, diameter ≥2 cm, onset at colon, and physiologically tubulovillous adenoma were the hazard factors causing high-grade adenoma risk in patients with intestinal polyp. Conclusion There are many risk factors causing high-grade adenoma in patients with intestinal polyp, and therefore, the screening for high-risk population shall be enhanced to reduce the potential of carcinomatous change in such patients.
Highlights
Intestinal polyps refer to protrusion lesions on the surface of the intestinal mucosa that protrude into the lumen and belong to an abnormally growing tissue that can occur anywhere in the intestine, with colonic polyps, rectal polyps, and colorectal polyps being the common types [1]
Investigations have revealed [5, 6] that intestinal polyps are the most predominant precancerous lesions of colorectal cancer; it is important for early detection, treatment, and follow-up of intestinal polyps
Intestinal carcinomatous change is related to the size, pathology, age, and other factors of adenomas, and its carcinogenesis time is about 10–15 years, which provides the temporal feasibility for early intervention in the malignant transformation of adenomatous polyps, and it is important to summarize the risk factors for the development of a high-grade risk of adenoma in patients with various types of intestinal polyps [7–9]. e current rule of colon polyp—adenoma—carcinomatous change has been generally accepted, so attention shall be paid to patients who have adenomatous polyps, and early detection and resection can reduce the risk of colorectal cancer to some extent
Summary
Intestinal polyps refer to protrusion lesions on the surface of the intestinal mucosa that protrude into the lumen and belong to an abnormally growing tissue that can occur anywhere in the intestine, with colonic polyps, rectal polyps, and colorectal polyps being the common types [1]. Adenomatous and nonadenomatous polyps are classified on the basis of pathologic biopsies, and the former is more prone to atypical hyperplasia and malignant change and, when underappreciated, may progress to colorectal cancer [2, 3]. Intestinal carcinomatous change is related to the size, pathology, age, and other factors of adenomas, and its carcinogenesis time is about 10–15 years, which provides the temporal feasibility for early intervention in the malignant transformation of adenomatous polyps, and it is important to summarize the risk factors for the development of a high-grade risk of adenoma in patients with various types of intestinal polyps [7–9]. E current rule of colon polyp—adenoma—carcinomatous change has been generally accepted, so attention shall be paid to patients who have adenomatous polyps, and early detection and resection can reduce the risk of colorectal cancer to some extent. The risk factors causing high-grade adenomas in patients with polyps were explored with the results reported as follows
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