Abstract

To refine estimates of how many persons in the United States are candidates for treatment of latent tuberculosis, we removed from analysis persons who self-reported prior treatment on the National Health and Nutrition Examination Survey 2011–2012. We estimate that 12.6 million persons could benefit from treatment to prevent active tuberculosis.

Highlights

  • To refine estimates of how many persons in the United States are candidates for treatment of latent tuberculosis, we removed from analysis persons who self-reported prior treatment on the National Health and Nutrition Examination Survey 2011–2012

  • Having already been treated for active TB or for latent TB infection (LTBI) was self-reported by 12.2% participants, or 1.8 million of the 14.1 million persons in the civilian, noninstitutionalized US population with a positive IGRA blood test result for TB infection

  • An estimated 12.6 million persons living in the United States with evidence of TB infection by IGRA result reported no prior TB treatment

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Summary

Introduction

To refine estimates of how many persons in the United States are candidates for treatment of latent tuberculosis, we removed from analysis persons who self-reported prior treatment on the National Health and Nutrition Examination Survey 2011–2012. To better estimate the number of persons in the United States who are candidates for LTBI treatment [8], we refined the NHANES-based estimate of the national LTBI prevalence by excluding from analysis persons who reported having received prior treatment for active TB or LTBI.

Results
Conclusion
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