Factores asociados a infección por Acinetobacter baumannii multidrogorresistente en unidad de cuidados intensivos. Estudio multicéntrico

Abstract

To analyze the factors associated with multidrug-resistant Acinetobacter baumannii (MDR-Ab) infection, treated at the intensive care unit (ICU) in the city of Trujillo, northern Peru. Case-control study in which 60 medical records of patients admitted to the ICU from three main hospitals in the city of Trujillo in northern Peru were reviewed, divided according to the presence or absence of multidrug-resistant A. baumannii infection (30 patients per group). The OR of the main postulated associated factors was calculated, then a multivariate analysis was performed. The average age was 60.3 and 46.3 years in patients with and without MDR-Ab respectively, being over 75 years old was significantly associated with MDR-Ab, prolonged ICU stay occurred in 90% of patients with Ab-MDR. MDR (OR: 13.5, p<0.001), hypoalbuminemia predominated in 86.7% of patients with MDR infection (OR: 4.33, p=0.041), 83.3% of patients with MDR-Ab were exposed to a central venous catheter (CVC) (OR:3.82; p=0.049), likewise, all patients had previous antibiotic therapy. Multivariate analysis showed that prolonged ICU stay (p=0.035) and CVC use (p=0.008) were independently associated with MDR-Ab infection. Prolonged stay in the ICU and the use of CVC are factors associated