Abstract
A 13-year-old boy had congenital factor XIII deficiency and a history of serious bleeding dating back to the neonatal period. He was successfully treated with monthly infusions of a single unit of plasma. It is concluded that all patients demonstrating factor XIII deficiency should be given a trial of monthly plasma infusion therapy. The diagnosis should be suspected for patients whose routine coagulation screening test results are normal, but in whom a history of significant bleeding episodes is obtained.
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