Abstract
Introduction: Hemostasis has been postulated as a mechanism of liver damage in cirrhosis. Low ADAMTS13/Von Willebrand Factor antigen (VWF:Ag) and high factor VIII/protein C ratio (FVIII/PC) mark platelet hyperaggregation (primary hemostasis) and hypercoagulation (secondary hemostasis), respectively. Aim: To explore the association of such parameters with the severity of the liver disease measured by Child-Pugh, MELD, MELD-Na and their prognostic role on clinical outcome.
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