Abstract
Diphtheria is an acute infectious disease caused by the Corynebacterium diphteriae bacteria. This bacterium will produce a toxin that spreads systemically and attacks the upper respiratory system and can cause damage to the respiratory epithelium. Diphtheria cases in Indonesia increased from 2016 to 2017 by 339 cases and caused outbreaks in Indonesia. The most cases are in East Java Province with the number reaching 48%. This research is a review study. The purpose of this study was to identify the studies that had been conducted related to factors that influence the diphtheria in East Java. The results of the review show the factors that influence the diphtheria in East Java are the level of education, immunization status, physical condition of the home, population density, occupancy density, level of knowledge, and personal hygiene.
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