Abstract
IT is now well known that at low levels of dietary protein, imbalances and excesses in the amino-acid content of the diet depress growth and food intake in rats. Increasing the casein-level from a value of 9 to 18 per cent eliminates the depression of appetite and the retardation of growth resulting from ingestion of a diet containing 3 per cent l-leucine1. In the work recorded here, we have examined the possibility that the higher basal protein level may act in part to increase the generalized capacity of the organism to metabolize and dispose of excess amino-acid loads.
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