Abstract

Abstract Synthesis of diverse N-arylphenylalanine derivatives through sequential transformations of N-arylphenylalanine ester-type platforms is disclosed. The highly functionalized platforms were prepared by an oxidative cross-coupling reaction leaving aryne generating moieties and halogeno groups intact. Great transformability of N-arylphenylalanine ester-type platforms by aryne reactions and cross-coupling reactions allowed us to prepare analogs of bioactive compounds.

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