Facile synthesis of polysubstituted furans and dihydrofurans via cyclization of bromonitromethane with oxodienes

Abstract

A series of polysubstituted furans and dihydrofurans have been prepared from readily available oxodienes and bromonitromethane in modest to excellent yields. This facile synthetic method is developed on the basis of proprietary properties of nitro group such as strong electron-withdrawing ability and cleavability. The conversion of nitro-substituted dihydrofurans to furans is presumably realized by elimination of HNO2 under the aid of DABCO.