Abstract
AbstractThe Suzuki‐type cross‐coupling reaction of arylboronic acids 3 with ethyl (Z)‐3‐iodo‐4,4,4‐trifluoro‐2‐butenoate 2, which was generated by hydroiodination of available ethyl 4,4,4‐trifluoro‐2‐butynoate 1, to afford ethyl (E)‐3‐aryl‐4,4,4‐trifluoro‐2‐butenoates 4, was studied for the first time. It was found that under the optimum conditions the cross‐coupling reaction could readily give 4 as the sole E‐isomer in 76–91% yields. © 2002 Wiley Periodicals, Inc. Heteroatom Chem 13:287–290, 2002; Published online in Wiley Interscience (www.interscience.wiley.com). DOI 10.1002/hc.10032
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