Facile sonochemical synthesis of rutile-type titanium dioxide microspheres decorated graphene oxide composite for efficient electrochemical sensor.

Abstract

In this reports the facile and green synthesis of rutile-type titanium dioxide nanoparticles decorated graphene oxide nanocomposite via the ultrasonication process (frequency: 50kHz, Power: 100W/cm2 and Ultrasonic type: Ti-horn). Because, the sonochemical synthesis method is simple, non-explosive and harmless method than other conventional technique. Furthermore, the synthesized material was characterized by various analytical techniques including FESEM, EDX, XRD, EIS and electrochemical methods. Then, the synthesized TiO2 MPs@GOS composite was applied for the electrocatalytic detection of theophylline (TPL) using CV and amperometric (current-time) techniques. Captivatingly, the modified sensor has excellent electrocatalytic performance with the wider linear range from 0.02 to 209.6µM towards the determination of theophylline and the LOD and sensitivity of the modified sensor was calculated as 13.26nM and 1.183μA·µM-1·cm-2, respectively. In addition, a selectivity, reproducibility and stability of the TiO2 MPs@GOS modified GCE were analyzed towards the determination of theophylline molecule. Finally, the real time application of TiO2 MPs@GOS modified theophylline sensor was established in serum and drug samples.