Abstract

Without any organic additives and metal ions,hollow hydroxyapatite(HAp)microspheres were successfully synthesized using hollow CaCO3 microspheres and Na2HPO4 as reactants. The hollow microspheres were characterized by scanning electron microscopy (SEM), field emission scanning electron microscope (FESEM) and X-ray diffraction (XRD). The results showed that the as-prepared HAp was hollow microspheres with diameter of 2-4 μm and were composed of many needle-like particles of 40-60 nm in diameter and 80-200 nm in length. The effects of synthesis conditions, such as reaction temperature, were studied. Furthermore, the reaction temperature has an important influence on the morphology of the hollow HAp microspheres. Based on this result, the formation mechanism of hollow HAp microspheres was discussed preliminarily.

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