Abstract

The oxy-vinyl alkoxides generated from trimethylsilyloxy-vinyl (or methoxyvinyl)-cyclobutanes by tetra-n-butylammonium fluoride undergo a facile[1, 3]shift to produce a two-carbon unit ring expansion compound under extremely mild conditions. Thus, 7-trimethylsilyloxy-7-vinyl (or methoxyvinyl)-2-azabicyclo[3.2.0]heptane-3, 4-diones readily gave hydroindole derivatives in good yields.

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