Facile engineering of gadolinium cobaltite anchored on functionalized carbon black as dynamic electrocatalyst for ultra-sensitive detection of nitroaromatic drug

Abstract

There has been a significant increase in the production and use of antibiotic drugs. However, the overuse and improper disposal of nitro-based antibiotics pose a significant threat to human health and the ecosystem. Specifically, the residues of antibiotic drugs such as nitrofurantoin (NFT) are dangerous to public health and pose a threat to the environment. In this study, we prepared a novel nanocomposite consisting of gadolinium cobaltite embedded functionalized carbon black (GdCoO3/f-CB) via a simple hydrothermal technique and utilized this nanocomposite as an electrode material for the electrochemical detection of NFT. The structural and morphological properties of the GdCoO3/f-CB nanocomposite was analyzed using a range of techniques, including XRD, Raman, XPS, EDX-Mapping, and HR-TEM. The electrocatalytic activity of the GdCoO3/f-CB nanocomposite was investigated using both CV and DPV techniques for the detection of NFT. Our results demonstrated that the prepared GdCoO3/f-CB nanocomposite delivered the excellent activities toward the detection of NFT at an extremely low limit of detection (LOD) of 2 nM and exhibited high sensitivity of 31 μA·μM−1·cm−2. Additionally, the proposed NFT sensor using GdCoO3/f-CB nanocomposite provided excellent reproducibility, repeatability, and selectivity, even in the presence of interfering molecules such as metal ions, biomolecules, and similar nitro compounds. These findings suggest that the GdCoO3/f-CB nanocomposite provides significant potential for the electrochemical detection of antibiotic drug residues for public health and the environment.