Facile design of wolframite type CoWO4 nanoparticles: A selective and simultaneous electrochemical detection of quercetin and rutin

Abstract

Facile construction of CWO/SPCE for electrochemical detection of QCT and RU. • Wolframite type CoWO 4 was synthesized by the facile one-step coprecipitation method. • CoWO 4 /SPCE showed improved performance for simultaneous detection of QCT and RU. • The proposed sensor demonstrated low LOD, high selectivity, and good stability. • Real-time analyses of QCT and RU was investigated in fruit juice sample. Flavonoids (FLs) have impressive attention in food-related items and medicinal areas because of their significant impact on the quality, function, and safety of the products. Thus, it is crucial to develop a simple and fast detection method for FLs in food and pharmaceutical samples. Consequently, we chose the rapid and cost-effective electrochemical detection method for FLs in a food sample. Herein, we report the facile design of wolframite type CoWO 4 (CWO) as an efficient electrocatalyst for simultaneous detection of quercetin (QCT) and rutin (RU). Crystallinity, structural morphology, and electrochemical investigations of CWO were characterized by using various spectrometric techniques and electroanalytical methods. The CWO modified screen-printed carbon electrode (SPCE), compared with a bare electrode demonstrated high electrochemically active surface area, better conductivity, and improved electrochemical sensing performance toward QCT and RU. Considering these advantages of CWO/SPCE, the optimized differential pulse voltammetric results showed the lowest detection limit of QCT as 0.022 µM and RU as 0.018 µM with the linear concentration of 0.2–521 µM (QCT) and 0.2–681 µM (RU). Significantly, CWO/SPCE displayed excellent selectivity for QCT and RU with effective interfering molecules, good stability (cyclic and storage), and reproducibility with five successive measurements. The practical analysis test was applied to QCT and RU in real fruit juice with the observed recoveries being acceptable.