Abstract
AbstractA practical method for the conversion of 1,2‐disubstituted cyclopropanols derived from Kulinkovich cyclopropanation into linear enones was developed. The approach features regioselective cleavage of the cyclopropane rings in EtOH at ambient temperature with inexpensive and readily available Co(acac)2 as the catalyst and air as the reagent. The crude intermediate peroxides were directly reduced with Ph3P to afford the corresponding β‐hydroxy ketones, which, on mesylation and β‐elimination performed in a one‐pot manner, furnished the end products in good to excellent yields after only one chromatography step at the end of the whole sequence.
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