Facile approach to synthesize magnesium oxide nanoparticles by using Clitoria ternatea—characterization and in vitro antioxidant studies

N John Sushma,T Madhavi,D Prathyusha,G Swathi,K Mallikarjuna,B Deva Prasad Raju,Hak-Sung Kim

doi:10.1007/s13204-015-0455-1

Abstract

Facile approach to synthesize the metal oxide nanoparticles is getting an increased attention in various biomedical applications such as, to treat antibiotic resistant diseases. Magnesium oxide nanoparticles (MgO·NPs) were synthesized by using Clitoria ternatea as the stabilizer in a green synthesis approach. The preliminary screening of MgO·NPs in the presence of C. ternatea extract was observed by UV–visible spectrophotometer. X-ray diffraction (XRD) pattern have proved the crystalline nature of the MgO·NPs; Photoluminescence (PL) measurement studies are used to identify the quality and defects in the crystal structure. FE-SEM with EDS has showed the size of 50–400 nm with specific binding energies. FT-IR has revealed the functional groups present in the plant extract and the peak at 521 cm−1 indicated the characteristic absorption bands of MgO·NPs. The DPPH activity and reducing power assay of biologically synthesized MgO·NPs could reach 65 % at a concentration of 150 µg/ml, respectively. From the results it was concluded that the biologically synthesized MgO·NPs exhibit good antioxidant activity.

Highlights

Over the recent years, green nanotechnology have attracted considerable spouting research in many potential limelight fields of nanoscience and nanomedicine, which is dedicated for the creation, improvement and utility of nanostructures for advanced biomedical science
This has led to our current research interest in synthesizing the metal oxide nanoparticles using ethanolic extract of Clitoria ternatea that consists of bioactive functional elements which act as reducing and protecting agent in green chemistry
The variable parameters such as dosage of C. ternatea extract, temperature and pH were measured with UV–visible spectrophotometer

Summary

Introduction

Green nanotechnology have attracted considerable spouting research in many potential limelight fields of nanoscience and nanomedicine, which is dedicated for the creation, improvement and utility of nanostructures for advanced biomedical science. Magnesium oxide nanoparticles (MgOÁNPs) were synthesized by using Clitoria ternatea as the stabilizer in a green synthesis approach.

Results

Conclusion