Fabrication of sensitive D-fructose sensor based on facile ternary mixed ZnO/CdO/SnO2 nanocomposites by electrochemical approach

Abstract

Abstracts In this approach, the nanocomposites (NCs) of ZnO/CdO/SnO2 were prepared by facile wet-chemical (co-precipitation) method in alkaline phase at low temperature. The synthesized ternary doped NCs were totally characterized in details by using various conventional methods, such as X-ray photoelectron spectroscopy (XPS), Field Emission Scanning Electron Microscopes (FESEM), Energy-dispersive X-ray spectroscopy (EDS) and powder X-ray diffraction (XRD). For the sensor application purpose, a glassy carbon electrode (GCE) was fabricated with ethanolic slurry of NCs by applying nafion adhesive (5% nafion suspension in ethanol) to result the D -fructose sensor by using electrochemical method at room conditions. A linear relation as current versus concentration of D -fructose was plotted to establish the calibration of D -fructose sensor, which is known as calibration curve. Remaking the linear segment on calibration curve, the linear dynamic range (0.1nM~0.01 mM) of D -fructose sensor was denoted. From the slope of the calibration curve and surface area of GCE (0.0316 cm2), the sensor sensitivity (28.4652 µA µM−1 cm−2) was calculated. Signal-noise ratio at 3 is used to calculated the lower limit (95.89 ± 4.79 pM) of D -fructose sensor. The analytical parameters such as response time, reproducibility, stability, validity, and repeatability of sensor were measured. Finally, the sensor was validated with real samples and found accepted and satisfactory results. Thus, the proposed method is inexpensive and simplest way to the development of reliable electrochemical sensor to detect chemicals and biochemicals in the field of food industry as well as health care sectors.