Abstract
Microneedle array electrodes (MNE) showed immense potential for the sensitive monitoring of the bioelectric signals by penetrating the stratum corneum with high electrical impedance. In this paper, we introduce a rigid parylene coated microneedle electrode array and portable electrocardiography (ECG) circuit for monitoring of ECG reducing the motion artifacts. The developed MNE showed stability and durability for dynamic and long-term ECG monitoring in comparison to the typical silver-silver chloride (Ag/AgCl) wet electrodes. The microneedles showed no mechanical failure under the compression force up-to 16 N, but successful penetration of skin tissue with a low insertion force of 5 N. The electrical characteristics of the fabricated MNE were characterized by impedance spectroscopy with equivalent circuit model. The designed wearable wireless ECG monitoring device with MNE proved feasibility of the ECG recording which reduces the noise of movement artifacts during dynamic behaviors.
Highlights
Cardiovascular disease (CVD) is the leading cause of death globally
Available Parafilm® M by (BemisTM, USA) was used to cover the Microneedle array electrodes (MNE) connection pad. parylene dimer Dichloro-p-xylene by (Daisan Kasei Co., Ltd., Ichihara, Japan) was used for insulation of MNE surface area and it was selected for its good insulation and safe biological properties
The MNE consisted of 3 × 5 microneedles at an interval interval of 700 μm
Summary
Cardiovascular disease (CVD) is the leading cause of death globally. More than 17.6 million people lost their life in 2016, and the number is expected to grow by over 23.6 million by the year2030. Cardiovascular disease (CVD) is the leading cause of death globally. The healthcare system suffers a major economic burden directly (e.g., hospitalization, physician visits, rehabilitation services, and drugs) and indirectly (e.g., long or short-term disabilities and premature mortality can cause losses in productivity) [1]. The risk factor for mortality and morbidity due to the novel infectious coronavirus disease (COVID-19) is higher for people with chronic health conditions. The pandemic COVID-19 has increased the demand for remote health-monitoring systems, especially for CVDs [2,3]. Sudden cardiac death and other heart problems can be avoided by using suitable prevention techniques, such as long-term monitoring of the heart signal and taking appropriate medication to prevent critical conditions [1]. An efficient long-term electrocardiography (ECG) monitoring technique is required to improve the accuracy of diagnosis of arrhythmia
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