Fabrication of nanostructured lipid carriers (NLC) for encapsulation of gac (Momordica cochinchinensis) oil by using homogenization method

Abstract

The aim of the study is to microencapsulate gac oil in solid lipid nanoparticles. Homogenization method was employed to produce microencapsulate particles. Following conditions were used: speed of 17500 rpm, assimilation time of 60 minutes at 80°C. The obtained particles had the smallest size of 103 nm. The ratio between gac oil and Stearic acid is 7.5% (v/v) and the ratio of solid lipid and oil is 8/2 (v/v) with the surfactant concentration Tween 80 of 3% (v/v). The particles are spherical with core-shell structure and the micro-encapsulated efficiency of Lycopene and β-Carotene are 65.28% and 70.13%, respectively. The obtained product was then stored in different conditions of thermal shock and temperature (10°C, ambient temperature and 45°C), with and without aluminum wrappings. Results showed that the color of the product changed slightly, and the solid lipid nanoparticles had very good stability without phase separation.