Abstract
Herein, biogenic silver nanoparticles, Cafi-AgNPs was produced based on Cassia fistula-phenolic-rich extract (Cafi) only, without any toxic chemical reagent or organic solvent. Cafi bioactives were characterized using UHPLC-ESI-QTOF-MS/MS analysis. The as-synthesized nanoparticles were characterized using physico-chemical techniques including UV–vis, TEM, SEM, EDX, FTIR, DLS, Zeta potential, XRD, TGA and DGA. In addition, their antioxidant properties and cytocompatibility on erythrocytes and HEK-293 cells were examined. Results show that Cafi mediated the successful synthesis of stable well-dispersed AgNPs. Cafi-AgNPs demonstrated potent reducing and radical scavenging activities against ABTS˙+, DPPH˙ and NO˙. Furthermore, Cafi-AgNPs was compatible with human erythrocytes and HEK-293 cells. Based on the superior surface plasmonic and biological attributes of Cafi-AgNPs, its potential in H2O2 sensing was evaluated. The proposed sensor demonstrated satisfactory analytical performances with linearity of 10–200 μM, detection limit of 3.0 μM for H2O2, and was successfully applied in the detection of H2O2 in human plasma.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
