Fabrication of hydroxyapatite nanoparticles decorated cellulose triacetate nanofibers for protein adsorption by coaxial electrospinning

Abstract

Abstract This contribution, for the first time, describes the preparation and characterization of hydroxyapatite (HAp) nanoparticles decorated cellulose triacetate (CTA) nanofibers for Bovine serum albumin (BSA) adsorption. CTA as core materials and HAp nanoparticles as sheath materials were used in nanofiber preparation. The chemical and morphological structures of CTA (core)-HAp (sheath) nanofibers were investigated by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Energy dispersive spectrometer (EDS), Fourier-transform infrared spectroscopy (FTIR). The prepared composite nanofibers were applied to adsorbing Bovine serum albumin (BSA), and the maximum equilibrium adsorption capacity (from Freundlich isotherm data) for BSA was 176.04 mg/g, which was higher than CTA nanofibers (18.39 mg/g). Thus the CTA (core)-HAp (sheath) nanofibers have the potential applications in the field of protein purification.