Abstract
The major challenge in utilizing pesticides lies in identifying the precise application that would improve the efficiency of these pesticides and decline their environmental and health hazards at the same time. Such application requires the development of specific formulations that enable controlled, stimuli-responsive release of the pesticides. Gelatin is a relatively cheap material characterized by temperature-sensitivity and abundant amino acid groups, which makes it suitable for the storage and controlled release of pesticides. In this study, gelatin microspheres were prepared by emulsion and cross-linking, then they were loaded with 2,4-dichlorophenoxyacetic acid sodium (2,4-D Na) as a model herbicide. To achieve temperature-tunable release of 2,4-D Na from the microspheres, NH4HCO3 was added to the formulations at different concentrations. The prepared formulations were characterized by SEM, FTIR, and size distribution analyzes, and their drug loading capacities were determined. Based on bioassay experiments, the 2,4-D Na-NH4HCO3-loaded gelatin microspheres can effectively control the spread of dicotyledonous weeds. Therefore, the strategy proposed herein can be used to develop novel, effective herbicide formulations.
Highlights
Due to technical limitations, full-text HTML conversion of this manuscript could not be completed
The major challenge in utilizing pesticides lies in identifying the precise application that would improve the efficiency of these pesticides and reduce their environmental and health hazards at the same time
Such application requires the development of specific formulations that enable controlled, stimuliresponsive release of the pesticides
Summary
Full-text HTML conversion of this manuscript could not be completed. Zheng Zhang Dalian University of Technology jun yang junyang@dlut.edu.cn This work is licensed under a Creative Commons Attribution 4.0 International Version of Record: A version of this preprint was published at Biotechnology Letters on July 18th, 2021.
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