Abstract

A highly sensitive glucose detection method was developed using functionalized carbon nanotube buckypaper as a free standing electrode in an electrochemical biosensor. Glucose oxidase was immobilized onto various buckypaper samples in order to oxidize glucose resulting in a measureable current/voltage signal output of the biosensor. Cyclic voltammetry (CV) and amperometry were utilized to determine the sensitivity of these buckypaper electrodes. Sensors of three different types of buckypaper were prepared and compared. These modified buckypaper electrode-based sensors showed much higher sensitivity to glucose compared to other electrochemical glucose sensors.

Highlights

  • Functionalized carbon nanotube (CNT) buckypapers (BP) were used in an effort to develop a highly sensitive glucose sensor

  • CNTs were modified by immersing into 1 L of a concentrated sulfuric acid-nitric acid mixture (a 3:1 ratio, i.e., 750 mL sulfuric acid to 250 mL nitric acid) for 8 h and stirred at 70 °C according to the conventional procedure [7]

  • The CNT backbone was shown for each around 1605 cm−1, and the unassigned peaks in each case are similar in each spectrum

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Summary

Introduction

Functionalized carbon nanotube (CNT) buckypapers (BP) were used in an effort to develop a highly sensitive glucose sensor. It has been reported that a relatively low level of glucose in blood would cause. Biosensors 2014, 4 hypoglycemia and could initiate epileptic seizure or even nerve damage [1]. Recent research reports suggest that it could trigger a heart attack due to very low sugar levels [2]. The determination of a low glucose level with high sensitivity was very important. This research described the effectiveness of modified CNT BP electrodes for the detection of glucose at relatively low levels. Buckypaper is a thin sheet (50–60 micron) of carbon nanotubes (CNTs), which is an advanced nanomaterial with outstanding electrochemical, piezoresistive, and mechanical properties. CNTs show a broad range of potential applications, such as lithium-ion batteries and solar cells [3]

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