Fabrication of a novel ZnO–CoO/rGO nanocomposite for nonenzymatic detection of glucose and hydrogen peroxide

Abstract

Herein, a novel nanocomposite of binary ZnO–CoO nanoparticles loaded on the graphene nanosheets (ZnO–CoO/rGO) has been successfully constructed via a facile, economical and two–step process. The obtained ZnO–CoO/rGO hybrids with high electrical conductivity and abundant active sites, could be modified on a glassy carbon electrode to detect glucose and H2O2 multi–functionally. The fabricated biosensor exhibits wide linear range for glucose (10μM to 11.205mM) and H2O2 (25μM to 11.1mM), and their corresponding sensitivity are 168.7μAmM−1cm−2 and 183.3μAmM−1cm−2. The limits of detection are 1.3μM and 0.44μM for the oxidation of glucose and the reduction of H2O2, respectively. Furthermore, remarkable selectivity, long–term stability and outstanding reproducibility of the non–enzyme biosensor prove that ZnO–CoO/rGO hybrids are the promising candidate in practical applications.