Abstract
Nanosilver particle has been used in the nanofiber mats by mixing the nanosilver with the spinning solution for improving the antibacterial property. Although studies have shown that the antibacterial property of nanofiber mats gets increasing, the higher silver content and the larger released resistance of nanosilver from nanofiber mats are obvious. Here, the electrospinning-combined postdeposition method was used to prepare the nanosilver/sericin/poly(ethylene oxide) (Ag/SS/PEO) nanofiber mats and the bacterial reduction rates againstStaphylococcus aureus(S. aureus) andEscherichia coli(E. coli) were analyzed. We found that the Ag/SS/PEO nanofiber mats were excellent antibacterial properties at the lower silver content and the bacterial reduction rates againstS. aureusandE. coliall reached above 99.99%. Our data suggests that the antibacterial property can be improved by introducing the electrospinning-combined postdeposition method.
Highlights
Nanosilver with the lower toxicity and the longer antibiotics time is a typical nanoantibiotic material in antibacterial agents [1, 2]
There is no efficient usage of nanosilver for nanofiber mats, especially for sericin nanofiber mats
We aim to explore whether electrospinningcombined postdeposition method is able to fabricate the nanosilver/sericin/poly(ethylene oxide) nanofiber mats and whether the new approach can improve the antibacterial property and obtain the super-antibacterial property nanofiber mats at the lower silver content
Summary
Nanosilver with the lower toxicity and the longer antibiotics time is a typical nanoantibiotic material in antibacterial agents [1, 2]. Mixing the nanosilver with the polymer solution prior to electrospinning is a general technique for nanofiber mats, as many studies have demonstrated favorable results in various nanofiber mats [3,4,5,6]. The resulting nanofiber mats by the general techniques still have some problems as biomedical materials. An additional concern with this polymer for improving sericin nanofiber forming property is that it has good biodegradability, biocompatibility, and spinnability. It has been proved that the nanofiber forming property can be greatly improved by adding PEO [11,12,13] This literature has reported that the keratin spinnability by adding the PEO is improved [14]
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